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Stress fiber strain recognition by the LIM protein testin is cryptic and mediated by RhoA

The actin cytoskeleton is a key regulator of mechanical processes in cells. The family of LIM domain proteins have recently emerged as important mechanoresponsive cytoskeletal elements capable of sensing strain in the actin cytoskeleton. The mechanisms regulating this mechanosensitive behavior, howe...

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Detalles Bibliográficos
Autores principales: Sala, Stefano, Oakes, Patrick W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684727/
https://www.ncbi.nlm.nih.gov/pubmed/34038160
http://dx.doi.org/10.1091/mbc.E21-03-0156