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p53 induces a survival transcriptional response after nucleolar stress

Accumulating evidence indicates that increased ribosome biogenesis is a hallmark of cancer. It is well established that inhibition of any steps of ribosome biogenesis induces nucleolar stress characterized by p53 activation and subsequent cell cycle arrest and/or cell death. However, cells derived f...

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Detalles Bibliográficos
Autores principales: Liao, Han, Gaur, Anushri, Mauvais, Claire, Denicourt, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684752/
https://www.ncbi.nlm.nih.gov/pubmed/34319761
http://dx.doi.org/10.1091/mbc.E21-05-0251