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Interplay of septin amphipathic helices in sensing membrane-curvature and filament bundling

The curvature of the membrane defines cell shape. Septins are GTP-binding proteins that assemble into heteromeric complexes and polymerize into filaments at areas of micron-scale membrane curvature. An amphipathic helix (AH) domain within the septin complex is necessary and sufficient for septins to...

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Detalles Bibliográficos
Autores principales: Woods, Benjamin L., Cannon, Kevin S., Vogt, Ellysa J. D., Crutchley, John M., Gladfelter, Amy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8684760/
https://www.ncbi.nlm.nih.gov/pubmed/34319771
http://dx.doi.org/10.1091/mbc.E20-05-0303