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TNFRSF11B Suppresses Memory CD4+ T Cell Infiltration in the Colon Cancer Microenvironment: A Multiomics Integrative Analysis

BACKGROUND: Colorectal cancer is a lethal cancer worldwide. Due to the low tumor mutation burden and low proportion of tumor-infiltrating lymphocytes in the microenvironment of most patients, innovative immunotherapeutic approaches need to be identified. METHODS: Using the TCGA-COAD dataset (n = 514...

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Detalles Bibliográficos
Autores principales: Zhang, Jun-rong, Hou, Ping, Wang, Xiao-jie, Weng, Zong-qi, Shang-guan, Xin-chang, Wang, Hui, You, Fang, Lin, Bing-qiang, Huang, Zheng-yuan, Chen, Xian-qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685235/
https://www.ncbi.nlm.nih.gov/pubmed/34938284
http://dx.doi.org/10.3389/fimmu.2021.742358