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Mitochondrial glutamine metabolism regulates sensitivity of cancer cells after chemotherapy via amphiregulin
The DNA damage response is essential for sustaining genomic stability and preventing tumorigenesis. However, the fundamental question about the cellular metabolic response to DNA damage remains largely unknown, impeding the development of metabolic interventions that might prevent or treat cancer. R...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685276/ https://www.ncbi.nlm.nih.gov/pubmed/34924566 http://dx.doi.org/10.1038/s41420-021-00792-7 |