Reunification of Object and View-Center Background Information in the Primate Medial Temporal Lobe

Recent work has shown that the medial temporal lobe (MTL), including the hippocampus (HPC) and its surrounding limbic cortices, plays a role in scene perception in addition to episodic memory. The two basic factors of scene perception are the object (“what”) and location (“where”). In this review, w...

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Autores principales: Chen, He, Naya, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685287/
https://www.ncbi.nlm.nih.gov/pubmed/34938164
http://dx.doi.org/10.3389/fnbeh.2021.756801
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author Chen, He
Naya, Yuji
author_facet Chen, He
Naya, Yuji
author_sort Chen, He
collection PubMed
description Recent work has shown that the medial temporal lobe (MTL), including the hippocampus (HPC) and its surrounding limbic cortices, plays a role in scene perception in addition to episodic memory. The two basic factors of scene perception are the object (“what”) and location (“where”). In this review, we first summarize the anatomical knowledge related to visual inputs to the MTL and physiological studies examining object-related information processed along the ventral pathway briefly. Thereafter, we discuss the space-related information, the processing of which was unclear, presumably because of its multiple aspects and a lack of appropriate task paradigm in contrast to object-related information. Based on recent electrophysiological studies using non-human primates and the existing literature, we proposed the “reunification theory,” which explains brain mechanisms which construct object-location signals at each gaze. In this reunification theory, the ventral pathway signals a large-scale background image of the retina at each gaze position. This view-center background signal reflects the first person’s perspective and specifies the allocentric location in the environment by similarity matching between images. The spatially invariant object signal and view-center background signal, both of which are derived from the same retinal image, are integrated again (i.e., reunification) along the ventral pathway-MTL stream, particularly in the perirhinal cortex. The conjunctive signal, which represents a particular object at a particular location, may play a role in scene perception in the HPC as a key constituent element of an entire scene.
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spelling pubmed-86852872021-12-21 Reunification of Object and View-Center Background Information in the Primate Medial Temporal Lobe Chen, He Naya, Yuji Front Behav Neurosci Neuroscience Recent work has shown that the medial temporal lobe (MTL), including the hippocampus (HPC) and its surrounding limbic cortices, plays a role in scene perception in addition to episodic memory. The two basic factors of scene perception are the object (“what”) and location (“where”). In this review, we first summarize the anatomical knowledge related to visual inputs to the MTL and physiological studies examining object-related information processed along the ventral pathway briefly. Thereafter, we discuss the space-related information, the processing of which was unclear, presumably because of its multiple aspects and a lack of appropriate task paradigm in contrast to object-related information. Based on recent electrophysiological studies using non-human primates and the existing literature, we proposed the “reunification theory,” which explains brain mechanisms which construct object-location signals at each gaze. In this reunification theory, the ventral pathway signals a large-scale background image of the retina at each gaze position. This view-center background signal reflects the first person’s perspective and specifies the allocentric location in the environment by similarity matching between images. The spatially invariant object signal and view-center background signal, both of which are derived from the same retinal image, are integrated again (i.e., reunification) along the ventral pathway-MTL stream, particularly in the perirhinal cortex. The conjunctive signal, which represents a particular object at a particular location, may play a role in scene perception in the HPC as a key constituent element of an entire scene. Frontiers Media S.A. 2021-12-06 /pmc/articles/PMC8685287/ /pubmed/34938164 http://dx.doi.org/10.3389/fnbeh.2021.756801 Text en Copyright © 2021 Chen and Naya. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Chen, He
Naya, Yuji
Reunification of Object and View-Center Background Information in the Primate Medial Temporal Lobe
title Reunification of Object and View-Center Background Information in the Primate Medial Temporal Lobe
title_full Reunification of Object and View-Center Background Information in the Primate Medial Temporal Lobe
title_fullStr Reunification of Object and View-Center Background Information in the Primate Medial Temporal Lobe
title_full_unstemmed Reunification of Object and View-Center Background Information in the Primate Medial Temporal Lobe
title_short Reunification of Object and View-Center Background Information in the Primate Medial Temporal Lobe
title_sort reunification of object and view-center background information in the primate medial temporal lobe
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685287/
https://www.ncbi.nlm.nih.gov/pubmed/34938164
http://dx.doi.org/10.3389/fnbeh.2021.756801
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