Cargando…

Developmental Exposure to a Human-Relevant Polychlorinated Biphenyl Mixture Causes Behavioral Phenotypes That Vary by Sex and Genotype in Juvenile Mice Expressing Human Mutations That Modulate Neuronal Calcium

Polychlorinated biphenyls (PCBs) are putative environmental risks for neurodevelopmental disorders. Here, we tested two hypotheses: (1) developmental exposure to a human-relevant PCB mixture causes behavioral phenotypes relevant to neurodevelopmental disorders; and (2) expression of human mutations...

Descripción completa

Detalles Bibliográficos
Autores principales: Sethi, Sunjay, Keil Stietz, Kimberly P., Valenzuela, Anthony E., Klocke, Carolyn R., Silverman, Jill L., Puschner, Birgit, Pessah, Isaac N., Lein, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685320/
https://www.ncbi.nlm.nih.gov/pubmed/34938155
http://dx.doi.org/10.3389/fnins.2021.766826