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Developmental Exposure to a Human-Relevant Polychlorinated Biphenyl Mixture Causes Behavioral Phenotypes That Vary by Sex and Genotype in Juvenile Mice Expressing Human Mutations That Modulate Neuronal Calcium
Polychlorinated biphenyls (PCBs) are putative environmental risks for neurodevelopmental disorders. Here, we tested two hypotheses: (1) developmental exposure to a human-relevant PCB mixture causes behavioral phenotypes relevant to neurodevelopmental disorders; and (2) expression of human mutations...
Autores principales: | Sethi, Sunjay, Keil Stietz, Kimberly P., Valenzuela, Anthony E., Klocke, Carolyn R., Silverman, Jill L., Puschner, Birgit, Pessah, Isaac N., Lein, Pamela J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685320/ https://www.ncbi.nlm.nih.gov/pubmed/34938155 http://dx.doi.org/10.3389/fnins.2021.766826 |
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