Therapeutic Drug Monitoring and Individualized Medicine of Dasatinib: Focus on Clinical Pharmacokinetics and Pharmacodynamics

Dasatinib is an oral second-generation tyrosine kinase inhibitor known to be used widely in Philadelphia chromosome-positive (Ph(+)) chronic myeloid leukemia (CML) and Ph(+) acute lymphoblastic leukemia (ALL). Notably, although a high pharmacokinetic variability in patients and an increased risk of...

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Detalles Bibliográficos
Autores principales: He, Shiyu, Bian, Jialu, Shao, Qianhang, Zhang, Ying, Hao, Xu, Luo, Xingxian, Feng, Yufei, Huang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685414/
https://www.ncbi.nlm.nih.gov/pubmed/34938198
http://dx.doi.org/10.3389/fphar.2021.797881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685414/
https://www.ncbi.nlm.nih.gov/pubmed/34938198
http://dx.doi.org/10.3389/fphar.2021.797881

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