A Novel Spider Toxin Inhibits Fast Inactivation of the Na(v)1.9 Channel by Binding to Domain III and Domain IV Voltage Sensors

Venomous animals have evolved to produce peptide toxins that modulate the activity of voltage-gated sodium (Na(v)) channels. These specific modulators are powerful probes for investigating the structural and functional features of Na(v) channels. Here, we report the isolation and characterization of...

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Detalles Bibliográficos
Autores principales: Peng, Shuijiao, Chen, Minzhi, Xiao, Zhen, Xiao, Xin, Luo, Sen, Liang, Songping, Zhou, Xi, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685421/
https://www.ncbi.nlm.nih.gov/pubmed/34938190
http://dx.doi.org/10.3389/fphar.2021.778534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685421/
https://www.ncbi.nlm.nih.gov/pubmed/34938190
http://dx.doi.org/10.3389/fphar.2021.778534

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