Effect of CYP3A4, CYP3A5, MDR1 and POR Genetic Polymorphisms in Immunosuppressive Treatment in Chilean Kidney Transplanted Patients

Cyclosporine (CsA) and tacrolimus (TAC) are immunosuppressant drugs characterized by a narrow therapeutic range and high pharmacokinetic variability. The effect of polymorphisms in genes related to the metabolism and transport of these drugs, namely CYP3A4, CYP3A5, MDR1 and POR genes, has been evalu...

Descripción completa

Detalles Bibliográficos
Autores principales: Contreras-Castillo, Stephania, Plaza, Anita, Stojanova, Jana, Navarro, Gustavo, Carmona, Rodolfo, Corvalán, Fernando, Cerpa, Leslie, Sandoval, Christopher, Muñoz, Daniel, Leiva, Marina, Castañeda, Luis E., Farias, Nayaret, Alvarez, Carolina, Llull, Gabriel, Mezzano, Sergio, Ardiles, Leopoldo, Varela, Nelson, Rodríguez, María S., Flores, Claudio, Cayún, Juan Pablo, Krall, Paola, Quiñones, Luis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685429/
https://www.ncbi.nlm.nih.gov/pubmed/34938174
http://dx.doi.org/10.3389/fphar.2021.674117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685429/
https://www.ncbi.nlm.nih.gov/pubmed/34938174
http://dx.doi.org/10.3389/fphar.2021.674117

Ejemplares similares