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Lysophosphatidic Acid and Several Neurotransmitters Converge on Rho-Kinase 2 Signaling to Manage Motoneuron Excitability

Intrinsic membrane excitability (IME) sets up neuronal responsiveness to synaptic drive. Several neurotransmitters and neuromodulators, acting through G-protein-coupled receptors (GPCRs), fine-tune motoneuron (MN) IME by modulating background K(+) channels TASK1. However, intracellular partners link...

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Detalles Bibliográficos
Autores principales: García-Morales, Victoria, Gento-Caro, Ángela, Portillo, Federico, Montero, Fernando, González-Forero, David, Moreno-López, Bernardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685439/
https://www.ncbi.nlm.nih.gov/pubmed/34938160
http://dx.doi.org/10.3389/fnmol.2021.788039