AKR1A1 Variant Associated With Schizophrenia Causes Exon Skipping, Leading to Loss of Enzymatic Activity

Schizophrenia is a heterogeneous psychiatric disorder characterized by positive symptoms such as hallucinations and delusions, negative symptoms such as anhedonia and flat affect, and cognitive impairment. Recently, glucuronate (GlucA) levels were reported to be significantly higher in serum of pati...

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Detalles Bibliográficos
Autores principales: Iino, Kyoka, Toriumi, Kazuya, Agarie, Riko, Miyashita, Mitsuhiro, Suzuki, Kazuhiro, Horiuchi, Yasue, Niizato, Kazuhiro, Oshima, Kenichi, Imai, Atsushi, Nagase, Yukihiro, Kushima, Itaru, Koike, Shinsuke, Ikegame, Tempei, Jinde, Seiichiro, Nagata, Eiichiro, Washizuka, Shinsuke, Miyata, Toshio, Takizawa, Shunya, Hashimoto, Ryota, Kasai, Kiyoto, Ozaki, Norio, Itokawa, Masanari, Arai, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685500/
https://www.ncbi.nlm.nih.gov/pubmed/34938315
http://dx.doi.org/10.3389/fgene.2021.762999

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685500/
https://www.ncbi.nlm.nih.gov/pubmed/34938315
http://dx.doi.org/10.3389/fgene.2021.762999

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