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Sensitivity of brain MRI and neurological examination for detection of upper motor neurone degeneration in amyotrophic lateral sclerosis

OBJECTIVES: To investigate sensitivity of brain MRI and neurological examination for detection of upper motor neuron (UMN) degeneration in patients with amyotrophic lateral sclerosis (ALS). METHODS: We studied 192 patients with ALS and 314 controls longitudinally. All patients visited our centre twi...

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Detalles Bibliográficos
Autores principales: Nitert, Abram D, Tan, Harold HG, Walhout, Renée, Knijnenburg, Nienke L, van Es, Michael A, Veldink, Jan H, Hendrikse, Jeroen, Westeneng, Henk-Jan, van den Berg, Leonard H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685620/
https://www.ncbi.nlm.nih.gov/pubmed/34663622
http://dx.doi.org/10.1136/jnnp-2021-327269