A single intranasal dose of a live-attenuated parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in hamsters

Single-dose vaccines with the ability to restrict SARS-CoV-2 replication in the respiratory tract are needed for all age groups, aiding efforts toward control of COVID-19. We developed a live intranasal vector vaccine for infants and children against COVID-19 based on replication-competent chimeric...

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Detalles Bibliográficos
Autores principales: Liu, Xueqiao, Luongo, Cindy, Matsuoka, Yumiko, Park, Hong-Su, Santos, Celia, Yang, Lijuan, Moore, Ian N., Afroz, Sharmin, Johnson, Reed F., Lafont, Bernard A. P., Martens, Craig, Best, Sonja M., Munster, Vincent J., Hollý, Jaroslav, Yewdell, Jonathan W., Le Nouën, Cyril, Munir, Shirin, Buchholz, Ursula J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685679/
https://www.ncbi.nlm.nih.gov/pubmed/34876520
http://dx.doi.org/10.1073/pnas.2109744118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685679/
https://www.ncbi.nlm.nih.gov/pubmed/34876520
http://dx.doi.org/10.1073/pnas.2109744118

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