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Biased M1 muscarinic receptor mutant mice show accelerated progression of prion neurodegenerative disease

There are currently no treatments that can slow the progression of neurodegenerative diseases, such as Alzheimer’s disease (AD). There is, however, a growing body of evidence that activation of the M1 muscarinic acetylcholine receptor (M1-receptor) can not only restore memory loss in AD patients but...

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Detalles Bibliográficos
Autores principales: Scarpa, Miriam, Molloy, Colin, Jenkins, Laura, Strellis, Bethany, Budgett, Rebecca F., Hesse, Sarah, Dwomoh, Louis, Marsango, Sara, Tejeda, Gonzalo S., Rossi, Mario, Ahmed, Zeshan, Milligan, Graeme, Hudson, Brian D., Tobin, Andrew B., Bradley, Sophie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685681/
https://www.ncbi.nlm.nih.gov/pubmed/34893539
http://dx.doi.org/10.1073/pnas.2107389118