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In vitro characterization of Haemonchus contortus trehalose-6-phosphate phosphatase and its immunomodulatory effects on peripheral blood mononuclear cells (PBMCs)

BACKGROUND: Trehalose-6-phosphate phosphatase (TPP6) is a key enzyme in the trehalose biosynthesis pathway. The accumulation of TPP6 inside the body is harmful to the pathogen, but almost nothing is currently known about the function of TPP6 from Haemonchus contortus (CRE-GOB-1). METHODS: The H. con...

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Detalles Bibliográficos
Autores principales: Wen, ZhaoHai, Xie, XinRan, Aleem, Muhammad Tahir, Aimulajiang, Kalibixiati, Chen, Cheng, Liang, Meng, Song, XiaoKai, Xu, LiXin, Li, XiangRui, Yan, RuoFeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685816/
https://www.ncbi.nlm.nih.gov/pubmed/34930417
http://dx.doi.org/10.1186/s13071-021-05115-4