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Arrhythmic Risk Assessment of Hypokalaemia Using Human Pluripotent Stem Cell-Derived Cardiac Anisotropic Sheets

Introduction: Hypokalaemia, defined as an extracellular concentration of K(+) below 3.5 mM, can cause cardiac arrhythmias by triggered or re-entrant mechanisms. Whilst these effects have been reported in animal and human stem cell-based models, to date there has been no investigation in more complex...

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Detalles Bibliográficos
Autores principales: Gurung, Bimal, Tse, Gary, Keung, Wendy, Li, Ronald A., Wong, Wing Tak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685904/
https://www.ncbi.nlm.nih.gov/pubmed/34938727
http://dx.doi.org/10.3389/fcell.2021.681665