Cargando…

Optimal control analysis of hepatocytic-erythrocytic dynamics of Plasmodium falciparum malaria

This paper presents an in-host malaria model subject to anti-malarial drug treatment and malaria vaccine antigens combinations. Pontryagin's Maximum Principle is applied to establish optimal control strategies against infected erythrocytes, infected hepatocytes and malaria parasites. Results fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Orwa, Titus Okello, Mbogo, Rachel Waema, Luboobi, Livingstone Serwadda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686038/
https://www.ncbi.nlm.nih.gov/pubmed/34977436
http://dx.doi.org/10.1016/j.idm.2021.11.006