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Optimal control analysis of hepatocytic-erythrocytic dynamics of Plasmodium falciparum malaria

This paper presents an in-host malaria model subject to anti-malarial drug treatment and malaria vaccine antigens combinations. Pontryagin's Maximum Principle is applied to establish optimal control strategies against infected erythrocytes, infected hepatocytes and malaria parasites. Results fr...

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Detalles Bibliográficos
Autores principales: Orwa, Titus Okello, Mbogo, Rachel Waema, Luboobi, Livingstone Serwadda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686038/
https://www.ncbi.nlm.nih.gov/pubmed/34977436
http://dx.doi.org/10.1016/j.idm.2021.11.006

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