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Optimal control analysis of hepatocytic-erythrocytic dynamics of Plasmodium falciparum malaria
This paper presents an in-host malaria model subject to anti-malarial drug treatment and malaria vaccine antigens combinations. Pontryagin's Maximum Principle is applied to establish optimal control strategies against infected erythrocytes, infected hepatocytes and malaria parasites. Results fr...
Autores principales: | Orwa, Titus Okello, Mbogo, Rachel Waema, Luboobi, Livingstone Serwadda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686038/ https://www.ncbi.nlm.nih.gov/pubmed/34977436 http://dx.doi.org/10.1016/j.idm.2021.11.006 |
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