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Implication of type 4 NADPH oxidase (NOX4) in tauopathy

Aggregates of the microtubule-associated protein tau are a common marker of neurodegenerative diseases collectively termed as tauopathies, such as Alzheimer's disease (AD) and frontotemporal dementia. Therapeutic strategies based on tau have failed in late stage clinical trials, suggesting that...

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Detalles Bibliográficos
Autores principales: Luengo, Enrique, Trigo-Alonso, Paula, Fernández-Mendívil, Cristina, Nuñez, Ángel, Campo, Marta del, Porrero, César, García-Magro, Nuria, Negredo, Pilar, Senar, Sergio, Sánchez-Ramos, Cristina, Bernal, Juan A., Rábano, Alberto, Hoozemans, Jeroen, Casas, Ana I., Schmidt, Harald H.H.W., López, Manuela G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686076/
https://www.ncbi.nlm.nih.gov/pubmed/34922273
http://dx.doi.org/10.1016/j.redox.2021.102210