Cargando…

In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure

OBJECTIVE: The Angiotensin 1 converting enzyme (ACE1) gene plays a critical role in regulating blood pressure and thus, it has become a major therapeutic target of antihypertensives. Single nucleotide polymorphisms (SNPs) occurring within a gene most especially at the functional segment of the genes...

Descripción completa

Detalles Bibliográficos
Autores principales: Udosen, Brenda, Soremekun, Opeyemi, Ekenna, Chinwe, Idowu Omotuyi, Olaposi, Chikowore, Tinashe, Nashiru, Oyekanmi, Fatumo, Segun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686250/
https://www.ncbi.nlm.nih.gov/pubmed/34930451
http://dx.doi.org/10.1186/s13104-021-05879-z