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In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure
OBJECTIVE: The Angiotensin 1 converting enzyme (ACE1) gene plays a critical role in regulating blood pressure and thus, it has become a major therapeutic target of antihypertensives. Single nucleotide polymorphisms (SNPs) occurring within a gene most especially at the functional segment of the genes...
Autores principales: | Udosen, Brenda, Soremekun, Opeyemi, Ekenna, Chinwe, Idowu Omotuyi, Olaposi, Chikowore, Tinashe, Nashiru, Oyekanmi, Fatumo, Segun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686250/ https://www.ncbi.nlm.nih.gov/pubmed/34930451 http://dx.doi.org/10.1186/s13104-021-05879-z |
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