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3C protease of enterovirus 71 cleaves promyelocytic leukemia protein and impairs PML-NBs production

BACKGROUND: Enterovirus 71 (EV71) usually infects infants causing hand-foot-mouth disease (HFMD), even fatal neurological disease like aseptic meningitis. Effective drug for preventing and treating EV71 infection is unavailable currently. EV71 3C mediated the cleavage of many proteins and played an...

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Detalles Bibliográficos
Autores principales: Li, Zhuoran, Wu, Ya’ni, Li, Hui, Li, Wenqian, Tan, Juan, Qiao, Wentao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686290/
https://www.ncbi.nlm.nih.gov/pubmed/34930370
http://dx.doi.org/10.1186/s12985-021-01725-7