How radical is radical cure? Site-specific biases in clinical trials underestimate the effect of radical cure on Plasmodium vivax hypnozoites

BACKGROUND: Plasmodium vivax blood-stage relapses originating from re-activating hypnozoites are a major barrier for control and elimination of this disease. Radical cure is a form of therapy capable of addressing this problem. Recent clinical trials of radical cure have yielded efficacy estimates r...

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Detalles Bibliográficos
Autores principales: Huber, John H., Koepfli, Cristian, España, Guido, Nekkab, Narimane, White, Michael T., Alex Perkins, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686294/
https://www.ncbi.nlm.nih.gov/pubmed/34930278
http://dx.doi.org/10.1186/s12936-021-04017-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686294/
https://www.ncbi.nlm.nih.gov/pubmed/34930278
http://dx.doi.org/10.1186/s12936-021-04017-1

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