A redox-responsive dihydroartemisinin dimeric nanoprodrug for enhanced antitumor activity

Redox-responsive drug delivery system emerges as a hopeful platform for tumor treatment. Dihydroartemisinin (DHA) has been investigated as an innovative tumor therapeutic agent. Herein, a DHA dimeric prodrug bridged with disulfide bond as linker (DHA(2)-SS) has been designed and synthesized. The pre...

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Detalles Bibliográficos
Autores principales: Li, Yawei, Pei, Qing, Cui, Baiji, Zhang, Hongmei, Han, Liu, Li, Wenqing, Zhu, Wenhe, Feng, Xianmin, Xie, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686335/
https://www.ncbi.nlm.nih.gov/pubmed/34930288
http://dx.doi.org/10.1186/s12951-021-01200-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686335/
https://www.ncbi.nlm.nih.gov/pubmed/34930288
http://dx.doi.org/10.1186/s12951-021-01200-z

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