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Brush swab as a noninvasive surrogate for tissue biopsies in epigenomic profiling of oral cancer

BACKGROUND: Oral squamous cell carcinoma (OSCC) has poor survival rates. There is a pressing need to develop more precise risk assessment methods to tailor clinical treatment. Epigenome-wide association studies in OSCC have not produced a viable biomarker. These studies have relied on methylation ar...

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Detalles Bibliográficos
Autores principales: Viet, Chi T., Zhang, Xinyu, Xu, Ke, Yu, Gary, Asam, Kesava, Thomas, Carissa M., Callahan, Nicholas F., Doan, Coleen, Walker, Paul C., Nguyen, Khanh, Kidd, Stephanie C., Lee, Steve C., Grandhi, Anupama, Allen, Clint T., Young, Simon, Melville, James C., Shum, Jonathan W., Viet, Dan T., Herford, Alan S., Roden, Dylan F., Gonzalez, Manuel L., Zhong, Jiang F., Aouizerat, Bradley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686381/
https://www.ncbi.nlm.nih.gov/pubmed/34930473
http://dx.doi.org/10.1186/s40364-021-00349-x