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HIV-1(LAI) Nef blocks the development of hematopoietic stem/progenitor cells into myeloid-erythroid lineage cells
BACKGROUND: A variety of hematopoietic abnormalities are commonly seen in human immunodeficiency virus-1 (HIV-1) infected individuals despite antiviral therapy, but the underlying mechanism remains elusive. Nef plays an important role in HIV-1 induced T cell loss and disease progression, but it is n...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686389/ https://www.ncbi.nlm.nih.gov/pubmed/34930406 http://dx.doi.org/10.1186/s13062-021-00317-3 |