Cargando…

Quantitative-enhancer-FACS-seq (QeFS) reveals epistatic interactions among motifs within transcriptional enhancers in developing Drosophila tissue

Understanding the contributions of transcription factor DNA binding sites to transcriptional enhancers is a significant challenge. We developed Quantitative enhancer-FACS-Seq for highly parallel quantification of enhancer activities from a genomically integrated reporter in Drosophila melanogaster e...

Descripción completa

Detalles Bibliográficos
Autores principales: Waters, Colin T., Gisselbrecht, Stephen S., Sytnikova, Yuliya A., Cafarelli, Tiziana M., Hill, David E., Bulyk, Martha L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686523/
https://www.ncbi.nlm.nih.gov/pubmed/34930411
http://dx.doi.org/10.1186/s13059-021-02574-x