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PEX-168 improves insulin resistance, inflammatory response and adipokines in simple obese mice: a mechanistic exploration

BACKGROUND: Polyethylene glycol loxenatide (PEX-168) is a new antidiabetic drug; as such, there are not yet any reports on its weight loss effect. Therefore, this trial was designed to investigate the effect of PEX-168 on simple obese mice. METHODS: Thirty healthy male C57BL/6 mice were randomly sel...

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Detalles Bibliográficos
Autores principales: Guo, Zeyuan, Wu, Yuting, Zhu, Lihua, Wang, Yong, Wang, Daorong, Sun, Xiaofang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686575/
https://www.ncbi.nlm.nih.gov/pubmed/34923973
http://dx.doi.org/10.1186/s12902-021-00908-1