Cargando…
PEX-168 improves insulin resistance, inflammatory response and adipokines in simple obese mice: a mechanistic exploration
BACKGROUND: Polyethylene glycol loxenatide (PEX-168) is a new antidiabetic drug; as such, there are not yet any reports on its weight loss effect. Therefore, this trial was designed to investigate the effect of PEX-168 on simple obese mice. METHODS: Thirty healthy male C57BL/6 mice were randomly sel...
Autores principales: | Guo, Zeyuan, Wu, Yuting, Zhu, Lihua, Wang, Yong, Wang, Daorong, Sun, Xiaofang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686575/ https://www.ncbi.nlm.nih.gov/pubmed/34923973 http://dx.doi.org/10.1186/s12902-021-00908-1 |
Ejemplares similares
-
Polyethylene Glycol Loxenatide (PEX-168) Reduces Body Weight and Blood Glucose in Simple Obese Mice
por: Wu, Yuting, et al.
Publicado: (2021) -
Polyethylene glycol loxenatide (PEX168) in subjects with renal impairment: A pharmacokinetic study
por: Wang, Jianwen, et al.
Publicado: (2019) -
A Mechanistic Perspective on PEX1 and PEX6, Two AAA+ Proteins of the Peroxisomal Protein Import Machinery
por: Pedrosa, Ana G., et al.
Publicado: (2019) -
The Role of Adipokines in Inflammatory Mechanisms of Obesity
por: Kirichenko, Tatiana V., et al.
Publicado: (2022) -
Pex11a deficiency causes dyslipidaemia and obesity in mice
por: Chen, Congcong, et al.
Publicado: (2018)