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P2Y12 receptor as a new target for electroacupuncture relieving comorbidity of visceral pain and depression of inflammatory bowel disease

BACKGROUND: The P2Y12 receptor is a kind of purinoceptor that is engaged in platelet aggregation, and P2Y12 inhibitors have been used in clinical antithrombotic therapy. The P2Y12 receptor in microglia induces interleukin-1β (IL-1β) expression, which is a key mediator of depression in the brain. Alt...

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Detalles Bibliográficos
Autores principales: Li, Yanzhen, Zhang, Hong, Yang, Jingwen, Zhan, Muouyang, Hu, Xuefei, Liu, Yongmin, Yu, Lingling, Yan, Xiaochen, Liang, Shangdong, Zhang, Ruyue, Lu, Ying, Li, Beining, Liu, Cunzhi, Li, Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686637/
https://www.ncbi.nlm.nih.gov/pubmed/34930362
http://dx.doi.org/10.1186/s13020-021-00553-9