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RLM: fast and simplified extraction of read-level methylation metrics from bisulfite sequencing data

SUMMARY: Bisulfite sequencing data provide value beyond the straightforward methylation assessment by analyzing single-read patterns. Over the past years, various metrics have been established to explore this layer of information. However, limited compatibility with alignment tools, reference genome...

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Detalles Bibliográficos
Autores principales: Hetzel, Sara, Giesselmann, Pay, Reinert, Knut, Meissner, Alexander, Kretzmer, Helene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686677/
https://www.ncbi.nlm.nih.gov/pubmed/34601556
http://dx.doi.org/10.1093/bioinformatics/btab663