Pre-Steady-State Kinetics of the SARS-CoV-2 Main Protease as a Powerful Tool for Antiviral Drug Discovery

The design of effective target-specific drugs for COVID-19 treatment has become an intriguing challenge for modern science. The SARS-CoV-2 main protease, M(pro), responsible for the processing of SARS-CoV-2 polyproteins and production of individual components of viral replication machinery, is an at...

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Detalles Bibliográficos
Autores principales: Zakharova, Maria Yu., Kuznetsova, Alexandra A., Uvarova, Victoria I., Fomina, Anastasiia D., Kozlovskaya, Liubov I., Kaliberda, Elena N., Kurbatskaia, Inna N., Smirnov, Ivan V., Bulygin, Anatoly A., Knorre, Vera D., Fedorova, Olga S., Varnek, Alexandre, Osolodkin, Dmitry I., Ishmukhametov, Aydar A., Egorov, Alexey M., Gabibov, Alexander G., Kuznetsov, Nikita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686763/
https://www.ncbi.nlm.nih.gov/pubmed/34938188
http://dx.doi.org/10.3389/fphar.2021.773198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686763/
https://www.ncbi.nlm.nih.gov/pubmed/34938188
http://dx.doi.org/10.3389/fphar.2021.773198

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