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Pre-Steady-State Kinetics of the SARS-CoV-2 Main Protease as a Powerful Tool for Antiviral Drug Discovery
The design of effective target-specific drugs for COVID-19 treatment has become an intriguing challenge for modern science. The SARS-CoV-2 main protease, M(pro), responsible for the processing of SARS-CoV-2 polyproteins and production of individual components of viral replication machinery, is an at...
Autores principales: | Zakharova, Maria Yu., Kuznetsova, Alexandra A., Uvarova, Victoria I., Fomina, Anastasiia D., Kozlovskaya, Liubov I., Kaliberda, Elena N., Kurbatskaia, Inna N., Smirnov, Ivan V., Bulygin, Anatoly A., Knorre, Vera D., Fedorova, Olga S., Varnek, Alexandre, Osolodkin, Dmitry I., Ishmukhametov, Aydar A., Egorov, Alexey M., Gabibov, Alexander G., Kuznetsov, Nikita A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686763/ https://www.ncbi.nlm.nih.gov/pubmed/34938188 http://dx.doi.org/10.3389/fphar.2021.773198 |
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