GADD34-mediated dephosphorylation of eIF2α facilitates pseudorabies virus replication by maintaining de novo protein synthesis

Viruses have evolved multiple strategies to manipulate their host’s translational machinery for the synthesis of viral proteins. A common viral target is the alpha subunit of eukaryotic initiation factor 2 (eIF2α). In this study, we show that global protein synthesis was increased but the eIF2α phos...

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Detalles Bibliográficos
Autores principales: Zhu, Ting, Jiang, Xueli, Xin, Hangkuo, Zheng, Xiaohui, Xue, Xiaonuan, Chen, Ji-Long, Qi, Baomin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686791/
https://www.ncbi.nlm.nih.gov/pubmed/34930429
http://dx.doi.org/10.1186/s13567-021-01018-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686791/
https://www.ncbi.nlm.nih.gov/pubmed/34930429
http://dx.doi.org/10.1186/s13567-021-01018-5

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