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Diazoxide Post-conditioning Activates the HIF-1/HRE Pathway to Induce Myocardial Protection in Hypoxic/Reoxygenated Cardiomyocytes

Background: Previous studies have shown that diazoxide can protect against myocardial ischemia-reperfusion injury (MIRI). The intranuclear hypoxia-inducible factor-1 (HIF-1)/hypoxia-response element (HRE) pathway has been shown to withstand cellular damage caused by MIRI. It remains unclear whether...

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Detalles Bibliográficos
Autores principales: Chen, Xi-Yuan, Wang, Jia-Qi, Cheng, Si-Jing, Wang, Yan, Deng, Meng-Yuan, Yu, Tian, Wang, Hai-Ying, Zhou, Wen-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687117/
https://www.ncbi.nlm.nih.gov/pubmed/34938777
http://dx.doi.org/10.3389/fcvm.2021.711465