Cargando…
An optimized genome-wide, virus-free CRISPR screen for mammalian cells
Pooled CRISPR screens have been widely applied to mammalian and other organisms to elucidate the interplay between genes and phenotypes of interest. The most popular method for delivering the CRISPR components into mammalian cells is lentivirus based. However, because lentivirus is not always an opt...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687118/ https://www.ncbi.nlm.nih.gov/pubmed/34935002 http://dx.doi.org/10.1016/j.crmeth.2021.100062 |