An Inhibitor of Grp94 Inhibits OxLDL-Induced Autophagy and Apoptosis in VECs and Stabilized Atherosclerotic Plaques

Background: Oxidized low-density lipoprotein (oxLDL) induces vascular endothelial cell (VEC) injury and atherosclerosis through activating endoplasmic reticulum stress. Expression of glucose-regulated protein 94 (Grp94) is induced by endoplasmic reticulum stress and Grp94 is involved in cardiovascul...

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Detalles Bibliográficos
Autores principales: Wei, Qun, Ren, Hui, Zhang, Jun, Yao, Wen, Zhao, Baoxiang, Miao, Junying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687133/
https://www.ncbi.nlm.nih.gov/pubmed/34938782
http://dx.doi.org/10.3389/fcvm.2021.757591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687133/
https://www.ncbi.nlm.nih.gov/pubmed/34938782
http://dx.doi.org/10.3389/fcvm.2021.757591

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