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Dynamic optimal experimental design yields marginal improvement over steady‐state results for computational maximisation of regulatory T‐cell induction in ex vivo culture

The isolation of T cells, followed by differentiation into Regulatory T cells (Tregs), and re‐transplantation into the body has been proposed as a therapeutic option for inflammatory bowel disease. A key requirement for making this a viable therapeutic option is the generation of a large population...

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Detalles Bibliográficos
Autores principales: Sinkoe, Andrew, Jayaraman, Arul, Hahn, Juergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Institution of Engineering and Technology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687199/
https://www.ncbi.nlm.nih.gov/pubmed/30472687
http://dx.doi.org/10.1049/iet-syb.2018.5014