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Dynamic optimal experimental design yields marginal improvement over steady‐state results for computational maximisation of regulatory T‐cell induction in ex vivo culture
The isolation of T cells, followed by differentiation into Regulatory T cells (Tregs), and re‐transplantation into the body has been proposed as a therapeutic option for inflammatory bowel disease. A key requirement for making this a viable therapeutic option is the generation of a large population...
Autores principales: | Sinkoe, Andrew, Jayaraman, Arul, Hahn, Juergen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Institution of Engineering and Technology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687199/ https://www.ncbi.nlm.nih.gov/pubmed/30472687 http://dx.doi.org/10.1049/iet-syb.2018.5014 |
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