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Revealing determinants of two‐phase dynamics of P53 network under gamma irradiation based on a reduced 2D relaxation oscillator model
This study proposes a two‐dimensional (2D) oscillator model of p53 network, which is derived via reducing the multidimensional two‐phase dynamics model into a model of ataxia telangiectasia mutated (ATM) and Wip1 variables, and studies the impact of p53‐regulators on cell fate decision. First, the a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Institution of Engineering and Technology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687238/ https://www.ncbi.nlm.nih.gov/pubmed/29337287 http://dx.doi.org/10.1049/iet-syb.2017.0041 |