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Ubiquitin chain specific auto‐ubiquitination triggers sustained oscillation, bistable switches and excitable firing

Ubiquitin modification of cellular proteins commonly targets them for proteosomal degradation, but can also convey non‐proteolytic functions. Over the past years, advances in experimental approaches have helped uncover the extensive involvement of ubiquitination in protein regulation. However, our u...

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Detalles Bibliográficos
Autores principales: Nguyen, Lan K., Zhao, Qi, Varusai, Thawfeek M., Kholodenko, Boris N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Institution of Engineering and Technology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687287/
https://www.ncbi.nlm.nih.gov/pubmed/25478702
http://dx.doi.org/10.1049/iet-syb.2014.0024