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Exploiting intrinsic fluctuations to identify model parameters

Parameterisation of kinetic models plays a central role in computational systems biology. Besides the lack of experimental data of high enough quality, some of the biggest challenges here are identification issues. Model parameters can be structurally non‐identifiable because of functional relations...

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Detalles Bibliográficos
Autores principales: Zimmer, Christoph, Sahle, Sven, Pahle, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Institution of Engineering and Technology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687306/
https://www.ncbi.nlm.nih.gov/pubmed/26672148
http://dx.doi.org/10.1049/iet-syb.2014.0010