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System‐based strategies for p53 recovery
The authors have proposed a systems theory‐based novel drug design approach for the p53 pathway. The pathway is taken as a dynamic system represented by ordinary differential equations‐based mathematical model. Using control engineering practices, the system analysis and subsequent controller design...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Institution of Engineering and Technology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687347/ https://www.ncbi.nlm.nih.gov/pubmed/29745903 http://dx.doi.org/10.1049/iet-syb.2017.0025 |