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Identification of a time‐varying intracellular signalling model through data clustering and parameter selection: application to NF‐ [Formula: see text] B signalling pathway induced by LPS in the presence of BFA

Developing a model for a signalling pathway requires several iterations of experimentation and model refinement to obtain an accurate model. However, the implementation of such an approach to model a signalling pathway induced by a poorly‐known stimulus can become labour intensive because only limit...

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Detalles Bibliográficos
Autores principales: Lee, Dongheon, Jayaraman, Arul, Sang‐Il Kwon, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Institution of Engineering and Technology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687386/
https://www.ncbi.nlm.nih.gov/pubmed/31318334
http://dx.doi.org/10.1049/iet-syb.2018.5079