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Identification of a time‐varying intracellular signalling model through data clustering and parameter selection: application to NF‐ [Formula: see text] B signalling pathway induced by LPS in the presence of BFA
Developing a model for a signalling pathway requires several iterations of experimentation and model refinement to obtain an accurate model. However, the implementation of such an approach to model a signalling pathway induced by a poorly‐known stimulus can become labour intensive because only limit...
Autores principales: | Lee, Dongheon, Jayaraman, Arul, Sang‐Il Kwon, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Institution of Engineering and Technology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687386/ https://www.ncbi.nlm.nih.gov/pubmed/31318334 http://dx.doi.org/10.1049/iet-syb.2018.5079 |
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