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Exosome-Mediated eCIRP Release From Macrophages to Induce Inflammation in Sepsis

Extracellular cold-inducible RNA-binding protein (eCIRP) is an important damage-associated molecular pattern (DAMP). Despite our understanding of the potentially harmful effects of eCIRP in sepsis, how eCIRP is released from cells remains elusive. Exosomes are endosome-derived extracellular vesicles...

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Detalles Bibliográficos
Autores principales: Murao, Atsushi, Tan, Chuyi, Jha, Alok, Wang, Ping, Aziz, Monowar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687456/
https://www.ncbi.nlm.nih.gov/pubmed/34938194
http://dx.doi.org/10.3389/fphar.2021.791648