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TopHap: Rapid inference of key phylogenetic structures from common haplotypes in large genome collections with limited diversity

MOTIVATION: Building reliable phylogenies from very large collections of sequences with a limited number of phylogenetically informative sites is challenging because sequencing errors and recurrent/backward mutations interfere with the phylogenetic signal, confounding true evolutionary relationships...

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Detalles Bibliográficos
Autores principales: Caraballo-Ortiz, Marcos A., Miura, Sayaka, Sanderford, Maxwell, Dolker, Tenzin, Tao, Qiqing, Weaver, Steven, Pond, Sergei L. K., Kumar, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687460/
https://www.ncbi.nlm.nih.gov/pubmed/34931186
http://dx.doi.org/10.1101/2021.12.13.472454