PermaPhos(Ser): autonomous synthesis of functional, permanently phosphorylated proteins

Installing stable, functional mimics of phosphorylated amino acids into proteins offers a powerful strategy to study protein regulation. Previously, a genetic code expansion (GCE) system was developed to translationally install non-hydrolyzable phosphoserine (nhpSer), with the γ-oxygen replaced with...

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Detalles Bibliográficos
Autores principales: Zhu, Phillip, Franklin, Rachel, Vogel, Amber, Stanisheuski, Stanislau, Reardon, Patrick, Sluchanko, Nikolai N., Beckman, Joseph S., Karplus, P. Andrew, Mehl, Ryan A., Cooley, Richard B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687462/
https://www.ncbi.nlm.nih.gov/pubmed/34931187
http://dx.doi.org/10.1101/2021.10.22.465468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8687462/
https://www.ncbi.nlm.nih.gov/pubmed/34931187
http://dx.doi.org/10.1101/2021.10.22.465468

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